Single administration of the same drug by intravenous and oral routes

Plasma concentration-time curves after a single administration of the same drug, whose bioavailability is 1 (100 %), by intravenous and oral routes.

Comparatively to intravenous administration, after oral administration, the Cmax is delayed and reduced but when the bioavailability is 100%, the AUC is the same.

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  Last update : September, 2006  
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