Statins and hypertension: do they have an antihypertensive effect?
| Author : Pierre Allain
||Date : 2010-4-30
Besides their lipid-lowering effect that is indisputable, pleiotropic effects such as anti-inflammatory and antihypertensive are attributed to statins.
A study published in the BMJ in March 2010 and called Phyllis shows that pravastatin at a dose of 40 mg per day for more than 2 years, does not enhance the antihypertensive effect of hydrochlorothiazide or fosinopril. In this study, systolic and diastolic blood pressure was measured clinically and in 24-hour ambulatory conditions.
This study shows that pravastatin and presumably other statins do not increase the effect of antihypertensive drugs.