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Statins and hypertension: do they have an antihypertensive effect?

Author : Pierre Allain Date : 2010-4-30

Besides their lipid-lowering effect that is indisputable, pleiotropic effects such as anti-inflammatory and antihypertensive are attributed to statins.

A study published in the BMJ in March 2010 and called Phyllis shows that pravastatin at a dose of 40 mg per day for more than 2 years, does not enhance the antihypertensive effect of hydrochlorothiazide or fosinopril. In this study, systolic and diastolic blood pressure was measured clinically and in 24-hour ambulatory conditions.

This study shows that pravastatin and presumably other statins do not increase the effect of antihypertensive drugs.


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