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Calcium, vitamin D and fractures

Author : Pierre Allain Date : 2010-1-24

The BMJ of January 12th, 2010 publishes a meta-analysis called Dipart from 7 clinical trials gathering 68 500 people concerning the prevention of fractures by a supplementation of vitamin D with or without calcium

This meta-analysis shows that vitamin D alone did not reduce the risk of fractures but the combination vitamin D plus calcium reduced it. This result reinforces the use of products containing 500 or 600 mg calcium and 400 international units, that is to say 10 µg, of vitamin D, generally D3 or cholecalciferol. This type of prescription is in agreement with the results of a French study, undertaken in women in 1992.

Actually, about a subject as common as the prevention of risk of fractures by calcium and vitamin D in the elderly of more than 65 years, literature data are complex and sometimes conflicting according to the parameters considered: all fractures, hip fractures, vertebral fractures, women or men, doses …

Many studies made until now did not take into account the baseline level of vitamin D; if a vitamin deficiency, affirmed by a blood determination, exists, the doses of vitamin D necessary are notably higher than the 10 or 20 micrograms daily...


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