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Omega-3 fatty acids and antidepressants (Sertraline)

Author : Pierre Allain Date : 2009-11-10

A paper published in the JAMA of October 21st, 2009 shows that in patients with major depression and coronary heart disease, the antidepressant treatment, during 10 weeks, with sertraline alone, Zoloft*, at the dose of 50 mg daily, is as effective as the treatment associating sertraline with the intake of omega-3 fatty acids (corresponding to 930 mg of eicosapentaenoic acid, EPA, and 750 mg of docosahexaenoic acid, DHA, daily).

The intake of omega-3 fatty acids, compared to corn oil used as placebo, did not increase the efficacy of sertraline to cure depression.

I don't know if there are studies reporting the effect of Mediterranean diets associated with antidepressant drugs.

More information about antidepressants.


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