Inhibitors of nucleotides biosynthesis

Taking into account the enzymatic reactions implicated in the synthesis of DNA and RNA that we have just pointed out, there are several possibilities to inhibit it. The drugs used to obtain this effect are inhibitors of folate synthesis, which theoretically have few adverse effects in humans, inhibitors of DHFR, inhibitors of thymidylate synthase, inosine monophosphate dehydrogenase and ribonucleotide diphosphate reductase.

Index for this chapter:

Your turn
User session
Bookmark, share this page
Bookmark and Share

  Last update : February 2009  
© 2000-2019 CdM Editions / P. Allain. All rights reserved
Pharmacorama Charter