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166 The plasma half-life of a drug is the tim...
167 A drug is given intravenously as a bolu...
168 Albumin:
169 Duringrepeated and regular administration...
170 A drug of chemical structure R-COOH whose...
171 An patient is treated continuously with a...
172 A drug whose plasma T1/2 is 24h is prescr...
173 A drug whose plasma T1/2 is 24h, is presc...
174 Three drugs A, B and C having different h...
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Quizz # : 174   Author : Pierre Allain

Three drugs A, B and C having different half-lives, A = 5 hours, B = 10 hours, C = 20 hours (but the same bioavailability  the same rate of intestinal absorption which is very fast and the same volume of distribution), are given by single administration at the same dose.Plasma concentrations are measured and concentration/time curves are plotted, area under curve, AUC, is calculated.
 A  The maximum plasma concentration, Cmax, of the drug C is 4 times higher than that of drug A
 B  The maximum plasma concentration, Cmax, of the drug B is about the same one as that of drug A
 C  The AUC of the drug B is the double of that of drug A
 D  The AUC of the drug C is identical to that of drug A
 E  The Tmax (time of the maximum concentration) of A, B and C are approximately the same

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All users stats, Q # 174
OK : 11 % NOK: 89 %
Out of 780 answers.
All users, easiest Q
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All users, toughest Q

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