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151 Bupropion or amfebutamone, Zyban*
152 Sibutramine, Sibutral*, Reductil*, Meridia*
153 Bosentan, Tracleer*,
154 Atosiban, Tractocile*,
155 Aprepitant, Emend*,
156 Pegvisomant, Somavert*,
157 In order to reduce the gastrointestinal a...
158 Ropinirole, Requip*, Adartrel*, are used...
159 Pergolide, Celance*, Permax*,
160 Teriparatide, Fortéo*,
161 P-glycoprotein:
162 The steady state concentration in plasma...
163 In pharmacokinetics, compartment:
164 By bioavailability one indicates in pharm...
165 The enzymatic inducing effect of a drug,...
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Quizz # : 173   Author : Pierre Allain

A drug whose plasma T1/2 is 24h, is prescribed orally  at the dose of 100mg once daily in the morning . At the end of 10 days of treatment, the clinical results and the plasma concentration of the drug are insufficient. The dose is doubled, 200mg daily, 100mg the morning and 100mg the evening. Following this change in treatment:
 A  Mean plasma concentration of the drug at the steady state doubles
 B  The drug plasma half-life doubles
 C  The difference between the maximum plasma concentration (peak) and minimal (trough) doubles
 D  The mean plasma concentration of the drug at the steady state
 E  The time required to reach the steady state of concentration is multiplied by 2

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All users stats, Q # 173
OK : 22 % NOK: 78 %
Out of 647 answers.
All users, easiest Q
72 - pril: the drugs whose international com...
166 The plasma half-life of a drug is the tim...
91 Diclofenac is
 

All users, toughest Q

70 Calcitonin
87 Diazoxide* is:
106 The drugs whose generic name (internation...
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