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151 Bupropion or amfebutamone, Zyban*
152 Sibutramine, Sibutral*, Reductil*, Meridia*
153 Bosentan, Tracleer*,
154 Atosiban, Tractocile*,
155 Aprepitant, Emend*,
156 Pegvisomant, Somavert*,
157 In order to reduce the gastrointestinal a...
158 Ropinirole, Requip*, Adartrel*, are used...
159 Pergolide, Celance*, Permax*,
160 Teriparatide, Fortéo*,
161 P-glycoprotein:
162 The steady state concentration in plasma...
163 In pharmacokinetics, compartment:
164 By bioavailability one indicates in pharm...
165 The enzymatic inducing effect of a drug,...
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Quizz # : 172   Author : Pierre Allain

A drug whose plasma T1/2 is 24h is prescribed orally at the dose of 100 mg once daily. At the end of 10 days of treatment, the clinical results and the plasma concentration of the drug are insufficient. The doctor doubles the dose, 200mg once daily (2 tablets of 100mg). Following this change in treatment:
 A  The mean plasma concentration doubles
 B  The plasma half-life of the drug doubles
 C  The difference between the maximum plasma concentration (peak) and minimal (trough) doubles
 D  the volume of distribution of the drug double
 E  The time required to reach the steady state of concenrtration decreases by a half

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All users stats, Q # 172
OK : 17 % NOK: 83 %
Out of 814 answers.
All users, easiest Q
72 - pril: the drugs whose international com...
166 The plasma half-life of a drug is the tim...
91 Diclofenac is
 

All users, toughest Q

70 Calcitonin
87 Diazoxide* is:
106 The drugs whose generic name (internation...
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